“Wunder von Elgg”: Vitamin D.
Aus professioneller Sicht gab es nur zwei realistische Erklärungen für das angebliche “Wunder von Elgg”: Eine Reihe falsch positiver PCR-Tests durch Laborkontamination (wie so oft ) oder eine erfolgreiche Prophylaxe bzw. Frühzeitige Behandlung.
Den Bericht gibt's hier. Aus der Studie Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data:
Results: We identified 25 eligible RCTs (a total of 11,321 participants, aged from 0 to 95 years). IPD were obtained for 10,933 out of 11,321 (96.6%) participants. Vitamin D supplementation reduced the risk of ARI among all participants [adjusted odds ratio (aor) 0.88, 95% confidence interval (ci) 0.81 to 0.96; heterogeneity p < 0.001]. Subgroup analysis revealed that protective effects were seen in individuals receiving daily or weekly vitamin D without additional bolus doses (aOR 0.81, 95% CI 0.72 to 0.91), but not in those receiving one or more bolus doses (aOR 0.97, 95% CI 0.86 to 1.10; p = 0.05). Among those receiving daily or weekly vitamin D, protective effects of vitamin D were stronger in individuals with a baseline 25-hydroxyvitamin D [25(oh)d] concentration of < 25 nmol/l (aOR 0.30, 95% CI 0.17 to 0.53) than in those with a baseline 25(OH)D concentration of ≥ 25 nmol/l (aOR 0.75, 95% CI 0.60 to 0.95; p = 0.006). Vitamin D did not influence the proportion of participants experiencing at least one serious adverse event (aOR 0.98, 95% CI 0.80 to 1.20; p = 0.83). The body of evidence contributing to these analyses was assessed as being of high quality.
Die Vitamin-D-Zugabe reduzierte das Risiko von akuten Atemwegsinfektionen bei allen Teilnehmern. […] Die Untergruppen-Analyse ergab, dass die schützenden Effekte bei den Teilnehmern auftraten, die täglich oder wöchentlich […] Vitamin D bekamen […]